Robert H. Rosa Jr., MD's 2011-2012 Basic and Clinical Science Course, Section 4: PDF

By Robert H. Rosa Jr., MD

ISBN-10: 1615251111

ISBN-13: 9781615251117

This quantity is split into elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific points. half I makes use of a hierarchy that strikes from common to express to assist derive a differential analysis for a selected tissue. half II is a compilation of chosen medical facets of significance to the final ophthalmologist. Following half II are the yank Joint Committee on melanoma 2010 staging kinds for ocular and adnexal tumors. This revised textual content comprises a number of new pathologic and scientific images. significant revision 2011-2012.

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Additional resources for 2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course)

Example text

C. Geographic proximity to the laboratory Molecu lar Techniqu es and Elect ron M icroscopy 1. Previous communication w ith ophthalmic pathologist to discuss a. Differential diagnosis b. Fixative (fresh vs alcohol vs glutaraldehyde vs oth er) c. Logistics of the biopsy i. Time and date (availabi lity of specia lized personnel) ii. Geographic proxim ity to laboratory chromogranin and synapto phys in fo r neuroendocrine lesions (metastatic carcinoid [see Fig 4-2], small cell carcinoma) leukocyte common antigen for lesions of hematopoi etic origin (leukemia, lymphoma) CD ant igens for subtypi ng white blood cells Her2 eu and c-Kit for prognosis and treatment (metastatic breast ca rci noma, mastocytosis) CHA PTER 4: Special Procedures.

Or molecular biological analysis (using peR on both fixed and non fixed material). Special fixatives are used for cytology specimens. The procedure is performed under direct visualization through a dilated pupil. Iris tumors may be accessible for FNAB duri ng slit-lamp biomicroscopy. However. FNAB alone cannot reliably predict the prognosis of a uveal melanoma because the sample with intraocular FNAB is limited. Intraocular FNA B may also enable tumor cells to escape the eye; this possibility is an area of some controversy.

Fresh tissue is critical. b. Adequate samp le is essenti al. c. Geographic proximity to the laboratory Molecu lar Techniqu es and Elect ron M icroscopy 1. Previous communication w ith ophthalmic pathologist to discuss a. Differential diagnosis b. Fixative (fresh vs alcohol vs glutaraldehyde vs oth er) c. Logistics of the biopsy i. Time and date (availabi lity of specia lized personnel) ii. Geographic proxim ity to laboratory chromogranin and synapto phys in fo r neuroendocrine lesions (metastatic carcinoid [see Fig 4-2], small cell carcinoma) leukocyte common antigen for lesions of hematopoi etic origin (leukemia, lymphoma) CD ant igens for subtypi ng white blood cells Her2 eu and c-Kit for prognosis and treatment (metastatic breast ca rci noma, mastocytosis) CHA PTER 4: Special Procedures.

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2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course) by Robert H. Rosa Jr., MD


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